High level a top line summary and key data

This product is a single-tablet combination that pairs a long-acting erectile dysfunction agent with a short-acting treatment for premature ejaculation. It is designed for adult men seeking simultaneous management of both conditions.

Typical international formulations seen online combine tadalafil 20 mg with dapoxetine 60 mg in one tablet. The rationale is to use tadalafil to support erectile function over many hours while dapoxetine, taken on demand, delays ejaculation for a shorter window around sexual activity.

Use the navigation above or jump straight to sections on dosing rhythm and timing, drug to drug positive interactions enhance user satisfaction., or Australian legal points for reference purposes only.

How does this work?

Tadalafil: a system relevant to erections

Tadalafil works by blocking the enzyme phosphodiesterase type 5 (PDE5). During sexual stimulation this increases blood flow into penile tissue and helps produce and maintain an erection. In many men a single dose may show activity for up to 36 hours.

Dapoxetine: the mechanism that drives it relevant to ejaculation control

Dapoxetine is a rapidly absorbed selective serotonin reuptake inhibitor given on demand to treat premature ejaculation in appropriate age groups. It modifies serotonin pathways involved in ejaculatory reflexes and usually reaches peak effect within about 40 to 50 minutes after taking it.

Use and administration guidance

Follow directions from your prescribing clinician or pharmacist. The points below are general and do not replace personalized medical advice.

  • Swallow the tablet whole with water; do not break, crush or chew it.
  • Take the tablet about 30 to 60 minutes before the time you expect sexual activity to allow both agents to become effective.
  • It may be taken with or without food, although large meals high in fat can delay the onset of effect.
  • Avoid excessive alcohol and grapefruit products because they may increase unintended effects or change blood levels of the medicines.
  • Remember tadalafil and dapoxetine reach peak levels at different times; plan dosing to match your needs for erection support and ejaculatory control.

If you are unsure whether this combination is appropriate for you or how to time a dose, speak in consultation with your prescriber. See more dose administration timing see more detail.

Dosing, timing and frequency

Use the lowest dose that gives an acceptable response and only for as long as clinically needed, under healthcare supervision.

  • Commonly marketed single-tablet strength internationally: tadalafil 20 mg combined with dapoxetine 60 mg, taken when needed prior to sexual activity.
  • Do not take more than one such tablet in any 24 hour period. Tadalafil can remain active for many hours, so frequency must be discussed with a clinician.
  • If you miss a planned dose, take it only if sexual activity will occur that same day; do not take two doses to make up for a missed one.
  • Some prescribers prefer issuing separate prescriptions for tadalafil and for a PE agent to allow dose adjustment of each component; ask about tailored approaches.

People with liver or kidney impairment or those taking interacting medicines may require dose modification or an a new possibility strategy. Always consult your prescriber for individualized dose calculation guidance offered.

Stowage and processing

  • Keep at room temperature, ideally between 20 to 25 degrees C (68 to 77 degrees F).
  • Store in a dry place away from strong heat and bright sunlight.
  • Keep all medicines out of reach and sight of children and animals.

Drug interaction alerts

Both components interact with other drugs and substances. Tell your prescriber or pharmacist about all medicines, supplements and recreational substances you use.

  • Nitrates or nitric oxide donors (for example glyceryl trinitrate, isosorbide dinitrate, nitroprusside, or alkyl nitrites): combining these with tadalafil can cause a dangerous drop in blood pressure and must not be done.
  • Alpha blockers and many blood pressure medicines: using these with tadalafil may cause symptomatic hypotension; timing and dose adjustments could be needed.
  • Strong CYP3A4 inhibitors (for example ketoconazole, itraconazole, ritonavir, cobicistat, clarithromycin): these can raise tadalafil and possibly dapoxetine concentrations and may require dose changes or avoidance.
  • CYP3A4 inducers (for example rifampicin, carbamazepine, phenytoin, St John’s wort): these may reduce effectiveness by increasing clearance.
  • Other serotonergic agents (SSRIs, SNRIs, MAO inhibitors, linezolid, lithium, some triptans): combining with dapoxetine raises the risk of serotonin syndrome.
  • Alcoholic drink product: may intensify dizziness, fainting, recurring headache and impairment. Avoid heavy drinking while taking this product.
  • Do not attach with other erectile dysfunction medicines without specific medical advice.

Ask your pharmacist to check for frequent intercommunications boost coordination. whenever you start or stop any medicine. See protective guidance, cautions, and cautions issued for extra safety data.

Alerts and safety first: steps to take

Do not take this combined tablet if any of the following apply to you:

  • Allergy to tadalafil, dapoxetine or any excipient in the tablet.
  • Severely impaired liver function or end-stage renal disease on dialysis.
  • Concurrent use of nitrates or recreational nitrite inhalants.
  • Recent major cardiac events such as a heart attack in the last 90 days, stroke within the last six months, unstable angina, severe heart failure or uncontrolled hypertension.

Tell your prescriber if you have a history of:

  • Blood disorders, bleeding problems, or conditions that increase the risk of prolonged erection.
  • Penile structural problems, significant heart disease, serious arrhythmias or valvular disease.
  • Neurological or psychiatric conditions including seizures, bipolar disorder, or previous low sodium (hyponatraemia).
  • Allergic reactions to medicines, herbal remedies or complementary products.

Practical safety notes: please review:

  • This medicine may cause dizziness, drowsiness or changes in vision; do not drive or operate machinery if affected.
  • If you experience chest pain, sudden severe episodic headache, sudden vision or hearing loss, fainting, or other alarming symptoms during sexual activity, stop and seek emergency medical help immediately.
  • This tablet does not prevent sexually transmitted infections; use barrier protection where appropriate.
  • The product is not indicated for women or for individuals under 18 years of age.
  • If an erection lasts longer than four hours, seek urgent medical attention to reduce the risk of permanent damage.

Negative responses and safety

Most harmful consequences are mild to moderate and settle without special treatment. Contact a healthcare professional if symptoms are severe, unexpected or persistent.

Commonly reported reactions include:

  • Head pain with facial flushing, and nasal congestion or a runny nose.
  • Dizziness spells, sleepiness or lightheadedness.
  • Gastrointestinal symptoms such as nausea, dry mouth, indigestion or diarrhea.
  • Persistent back pain, muscle aches, difficulty sleeping or increased restlessness.

Less common but potentially serious events — seek immediate care if these occur:

  • An erection that remains painful for more than four hours (priapism).
  • Severe hypersensitivity reactions causing swelling of the face, lips, tongue or throat, and breathing difficulties.
  • Sudden vision loss or sudden decrease in hearing, sometimes with tinnitus and dizziness.
  • Signs of serotonin syndrome when dapoxetine is combined with other serotonergic drugs: agitation, high temperature, sweating, tremor, muscle rigidity, confusion or fast heartbeat.

Different options and comparable therapies

If a prepackaged combination tablet is not suitable, clinicians often consider single active agents or non-drug interventions. Selection depends on medical historypromise interpersonal dialogue and exchanges can be viewed as exchanges of information., patient preference and local availability.

Approaches to treating erectile dysfunction

  • Tadalafil alone: available as on-demand 10 to 20 mg doses or low-dose daily regimens such as 2.5 to 5 mg.
  • Sildenafil (generic or Viagra): a shorter acting PDE5 inhibitor commonly used first-line.
  • Vardenafil (Levitra): an the other option PDE5 inhibitor for some men.
  • Spedra (Avanafil): may have faster onset; availability in Australian pharmacies varies.
  • Non-oral approaches: vacuum erection devices or intracavernosal injections such as alprostadil for men who cannot use or do not respond to oral agents.

Medical options for premature ejaculation

  • Dapoxetine for on-demand use where it is licensed and accessible.
  • Topical anesthetics (lidocaine or prilocaine creams and sprays) to decrease penile sensitivity.
  • Behavioural techniques such as stop-start, squeeze methods and pelvic floor exercises.
  • Daily oral SSRIs used off-label for PE in some cases, for example sertraline or paroxetine, when prescribed by a clinician.

Talk with an Australian registered prescriber about which option best suits you. See fee schedule estimates and notes on legality to elaborate with more context.

Australian dollar price projections

Australian retail prices vary by brand, pack size, pharmacy and whether a product is subsidised. The approximate ranges below are indicative only and should be checked locally.

  • Generic tadalafil (10 to 20 mg): roughly AUD 1.50 to AUD 6.50 per tablet when bought in larger quantities; branded Cialis tablets can cost around AUD 18 to AUD 30 each depending on pack size.
  • Sildenafil 50 to 100 mg: generics often cost around AUD 0.80 to AUD 4.50 per tablet; branded Viagra frequently retails between AUD 12 and AUD 30 per tablet.
  • Spedra is Avanafil 50 to 200 mg: where stocked, standard prices range from about AUD 8 to AUD 22 per tablet.
  • Topical lidocaine/prilocaine products for premature ejaculation: commonly AUD 18 to AUD 50 per pack depending on strength and size.
  • Dapoxetine 30 to 60 mg: not widely available through Australian community pharmacies; overseas listings may show AUD 3 to AUD 12 per tablet but importing brings legal and safety risks.
  • Fixed-dose tadalafil 20 mg plus dapoxetine 60 mg from international sellers often display prices between AUD 6 and AUD 16 per tablet; availability and legality in Australia vary greatly.

Confirm current pricing approach and prescription requirements with your local pharmacist before purchase. Note that most erectile dysfunction medicines are prescription-only and are not commonly subsidised on the PBS for this indication.

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