Survey of the headic
Mirtazapine prescription, commonly sold under the brand name Remeron, is an antidepressant frequently prescribed for major depressive disorder. It is often chosen when patients have insomnia or poor appetite because mirtazapine can produce sedation and stimulate appetite.
From a cursory glance:
- The core active ingredient is mirtazapine.
- Class: antidepressant - noradrenergic and specific serotonergic agent
- Common tablet strengths available in Australia: 7.5 mg, 15 mg, 30 mg
Fast links: check the dynamic pricing estimatesreview other treatment options, or see the regulatory details to the advantage of Australia.
First, prepare yourself
Discuss the following with your prescriber or pharmacist before starting mirtazapine. Inform them about any of these conditions or circumstances:
- Medical history of bipolar disorder with mania or hypomania
- Long-term kidney disease or liver impairment
- Current or past suicidal thoughts, self-harm, or sudden mood changes
- Known allergy to mirtazapine or any tablet excipients
- Pregnancy, or planning to conceive, or breastfeeding.
If you are unsure whether a particular condition is important, ask your healthcare professional. Prescribing for children and adolescents requires careful specialist assessment and surveillance of system activity.
How to absorb what happened
Follow the dosing instructions with cautions on your prescription exactly. Mirtazapine prescription is usually taken once each day, often at night because of its sedating effects. Swallow the pills intact with water.
Keep to a consistent schedule. Do not alter your dose or stop therapy suddenly without medical advice; when discontinuation is necessary your prescriber will usually recommend a gradual dose reduction to reduce withdrawal symptoms.
When an deliberate overdose occurs or if you are in immediate danger call emergency services on 000 and contact the Poisons Information Centre at 13 11 26 for urgent advice.
Dose was missed
If you miss taking one dose, take it as soon as you remember unless the next dose is due within four hours. If the next dose is less than four hours away, skip the i skipped the dose and continue your usual schedule. Do not double your dose to compensate for a missed tablet.
Medicines, supplements and substances that may interact
Several medicines and complementary products can interact with mirtazapine. Do not bring together it with:
- Monoamine oxidase inhibitors (MAOIs) such as phenelzine, tranylcypromine or selegiline
- Procarbazine in cancer treatment
- St John s wort (Hypericum perforatum)
- Tryptophan supplement offerings
Use caution and seek advice if you are taking any of the following:
- Other antidepressants or antipsychotic drugs
- Benzodiazepines, strong opioids or other medicines that cause sedation
- Medications that may lengthen the QT interval on ECG
- Strong CYP3A4 inhibitors or inducers
These lists are not exhaustive. Provide your prescriber and pharmacist with a complete list of prescription medicines, over-the-counter products, herbal remedies, alcohol intake and any recreational drugs you use.
Vigilant monitoring procedures and measures for safety
- The antidepressant effect may take several weeks to become apparent. Continue therapy until your clinician evaluates your response and advises otherwise.
- Be alert for any worsening mood, increased anxiety, agitation, unusual behaviour or suicidal thoughts, especially when starting or changing dose. Seek immediate help if these occur.
- Mirtazapine formulation can cause drowsiness or lightheadedness. Do not drive or operate heavy machinery until you know how it affects you. Rise slowly from sitting or lying positions to reduce dizziness.
- Avoid alcohol while taking mirtazapine as it can increase sedation and impair judgement.
- Speak to a pharmacist before using non-prescription cough, cold or allergy remedies since some may increase drowsiness or interact.
- Simple measures such as sugar-free gum, sucking lozenges or staying well hydrated can relieve dry mouth; seek professional help if symptoms continue.
What incidental outcomes may occur and when to reach out for help
If you experience a health emergency, seek urgent medical attention. any serious or potentially life-threatening signs, including:
- Severe allergic reactions: rash, hives, swelling of the face, lips or tongue, or breathing difficulty
- High fever, sore throat, mouth ulcers or blistering
- Flu-like symptoms with widespread muscle or joint pain
- Severe abdominal pain lasting hours with persistent vomiting or nausea
- Marked confusion, severe agitation or thoughts of self-harm
- Sudden swelling of hands, ankles or feet
- Unexplained bleeding, easy bruising or extreme fatigue
Usually mild lingering effects that are common that may improve over time include constipation, increased appetite and weight gain, drowsiness or dizziness, and dry mouth. If lingering effects persist or interfere with daily life, speak to your prescriber or pharmacist to consider management options or a new possibility treatment options.
Storage module and disposal of waste
- Keep medicines away from kids, out of reach and out of sight.
- Store between 15 and 30 degrees C in a dry place away from strong light.
- Do not use medicine beyond the expiry date shown on the pack.
- Return unwanted or expired medicines to a participating pharmacy for safe disposal via community collection programs; do not throw medicines in household rubbish or pour them down drains.
Medicines that are substitutes and comparable
Depending on the clinical needs and side effect preferences, prescribers may select other antidepressant classes. Core a different route options in Australia include:
- SSRIs: sertraline, escitalopram, citalopram, fluoxetine, paroxetine
- Venlafaxine, desvenlafaxine, and duloxetine belong to the SNRI category.
- Other options: bupropion, vortioxetine, agomelatine, or tricyclic antidepressants such as amitriptyline and nortriptyline
Mirtazapine antidepressant tends to be more sedating and more likely to increase appetite and weight than many SSRIs or SNRIs. This can be an advantage when insomnia or poor appetite are prominent but a disadvantage if weight gain is a concern. Discuss benefits and drawbacks with your clinician when comparing choices.
For a brief a quick price comparison see the price list area, or revert to the a gist of the main points for basic facts.
Common discount pricing in Australia (AUD)
Price depends on pharmacy, brand, pack size and whether the Pharmaceutical Benefits Scheme (PBS) subsidy applies. Figures below are estimates for illustration and may change.
- Private purchase (generic): a 30-tablet pack of generic mirtazapine 15 mg or 30 mg typically costs approximately AUD 10 to AUD 45 depending on supplier and brand.
- Brand Remeron without subsidy is usually toward the higher end of the private purchase range.
- PBS-subsidised prescriptions: if mirtazapine and your clinical indication meet PBS criteria the patient contribution may be around AUD 31 for general patients and about AUD 7 for concession card holders; these amounts are subject to change and annual updates.
For current, exact prices contact local pharmacies or consult PBS listings online. Notice the legal and regulatory compliance section for notes on subsidies and prescription rules.
Regulatory information about Australia and its laws
- Regulatory status: mirtazapine is a Schedule 4 prescription-only medicine regulated by the Therapeutic Goods Administration (TGA).
- Prescription requirements: a valid prescription from an Australian-registered prescriber is required; many pharmacies accept electronic prescriptions and telehealth prescriptions from authorised prescribers.
- PBS listing: certain strengths and brands of mirtazapine may be listed on the PBS. Eligibility, signals pointing to and patient co-payments depend on current listings and individual circumstances.
- Personal importation: under TGA personal importation provisions an individual can import up to a three-month personal supply with a valid prescription for personal use; commercial importation without licences is not permitted.
- Driving and safety: it is illegal to drive while impaired by medication. Because mirtazapine can cause drowsiness, assess your response before driving or operating machinery.
- Misuse and diversion: sharing, selling or giving prescription medicines to others is unlawful. Keep prescriptions and medication secure to prevent misuse.
- Disposal: participate in community medicine return schemes such as Return Unwanted Medicines for safe disposal rather than disposing via household rubbish or wastewater.
For official guidance consult the TGA and PBS websites or speak with your pharmacist. If you are considering importing medicine for personal useplease validate. the current TGA personal importation guidance before proceeding.
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