What this product is designed to be used for

Extra Super Tadarise is marketed in some countries as a single-tablet combination intended to address two male sexual health issues at the same time: erectile dysfunction and premature ejaculation. The tablet pairs tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor that helps sustain erections during sexual stimulation, with dapoxetine, a short-acting selective serotonin reuptake inhibitor (SSRI) used in some markets to delay ejaculation.

This page has been written with readers in the United States in mind and summarizes composition, practical safety measures to implement, price references in US dollars, in addition to the legal standing of these drugs in the US. See price level details Typical costs in the United States (USD). For legislation and regulatory oversight context see Legal and regulatory matters in the USA.

  • Main goal: combined management of erectile dysfunction and premature ejaculation in adult men after clinical assessment.
  • Not intended for sports performance or recreational use.
  • Information here is educational and does not replace medical evaluation and prescription.

Active elements and typical doses

Products sold under the Extra Super Tadarise name usually contain two active ingredients in a fixed ratio. The most commonly reported formulation includes:

  • Dapoxetine 60 mg pill — a short-acting SSRI used in several countries to delay ejaculation.
  • 40 milligrams of tadalafil — a PDE5 inhibitor that supports erection by increasing penile blood flow during arousal.

Commercial presentations often advertise one tablet with 40 mg tadalafil plus 60 mg dapoxetine. Doses and combinations vary by manufacturer in markets where such products are sold.

Who would gain

This combination is intended for adult men who have a confirmed diagnosis of both erectile dysfunction and premature ejaculation following clinical evaluation. It is not appropriate for self-diagnosis or unsupervised use.

  • Erectile dysfunction defined as the inability to achieve or maintain an erection sufficient for satisfactory sexual activity.
  • Premature ejaculation defined as ejaculation occurring sooner than desired and causing distress or difficulty in relationships.

Always consult a licensed clinician to confirm diagnoses and to select a treatment plan tailored to individual medical history and preferences.

Administration and dosing guidelines

Follow the directions provided by your healthcare professional. The guidance below summarizes common points for as-needed use, which is how combination tablets of this type are typically taken:

  • Take the exact dose prescribed; do not exceed the recommended amount.
  • Swallow whole with water. Do not chew, crush, or split unless the product is explicitly formulated for division.
  • It can be taken with or without meals. Heavy, fatty meals can delay how quickly the medicine takes effect.
  • Timing commonly recommended is about one hour before planned sexual activity, but onset varies between individuals.
  • If you are placed on a regular schedule rather than on-demand dosing, follow your prescriber and do not double up after a dose was not taken.

If you have kidney or liver impairment, dosing adjustments may be required; discuss this in partnership with your prescriber.

Safety notes and cautions

Prior to starting any medication that affects blood pressure, erection physiology, or neurotransmitters, provide your clinician with a complete medical and medication history. Particular caution is required in the following situations:

  • Do not self-treat—obtain medical assessment to exclude other causes of sexual dysfunction.
  • Not for anyone younger than 18 years.
  • Older adults may require closer continuous monitoring and tailored dosing.
  • Both tadalafil and dapoxetine can lower blood pressure and cause lightheadedness, dizziness, or fainting.
  • Men with structural penile abnormalities (for example, Peyronie disease) or blood disorders that predispose to priapism need specialist advice.
  • Severe liver or kidney disease can change how the drugs are handled by the body and often requires specialist oversight.
  • Stop the medication and seek emergency care for sudden vision loss, sudden hearing loss, severe chest pain, fainting, or an erection lasting longer than four hours.

In what cases not to use it

  • Known hypersensitivity to tadalafil, dapoxetine, or any tablet excipient.
  • Concurrent use of nitrates or nitric oxide donors, including recreational poppers, because of risk of severe hypotension.
  • People under 18 years old.
  • Uncontrolled low blood pressure or recent episodes of syncope due to hypotension.
  • Uncontrolled or severe cardiac conditions unless cleared by a cardiologist.
  • Severe, uncontrolled seizure disorder or active serious psychiatric illness without supervision.
  • Current use of monoamine oxidase inhibitors (MAOIs) or certain other antidepressants unless managed by a specialist; see Reciprocal the act of connecting with otherss fuel collaboration and innovation..
  • Significant bleeding disorders or conditions that increase risk of priapism.

Frequently occurring serious incidental effects

Not everyone will experience adverse reactions. Frequently reported effects associated with tadalafil and dapoxetine include:

  • Flushed face accompanying migraine like headache, and sensations of warmth
  • Nasal stuffiness or rhinorrhea
  • Tiredness, dizziness, or drowsiness
  • Nausea, indigestion, or dry mouth
  • Pain in the back or aching muscles
  • Chronic sweating and decreased sexual desire in some cases
  • Blood pressure reductions that may lead to fainting in rare instances

Seek life saving medical care for a serious injury chest discomfort, severe fainting, allergic reactions, sudden loss of sight or hearing, or an erection that persists beyond four hours.

Significant frequent the process of interactions boost coordination. between prescribed drugs and foods

Both components have clinically relevant collaborative interactions are not just about words, but meaning.. Review all current prescriptions, over-the-counter drugs, and supplements with your prescriber and pharmacist.

  • Nitrates: combining nitrates with PDE5 inhibitors can cause dangerous drops in blood pressure. Never combine these.
  • Riociguat and other pulmonary hypertension agents: additive hypotensive effects are possible.
  • Certain antidepressants and MAO inhibitors: combining with dapoxetine can increase the risk of serotonin-related adverse events.
  • CNS depressants such as sedatives and opioids: may worsen drowsiness and respiratory depression.
  • Strong CYP3A4 inhibitors (for example some antifungals, macrolide antibiotics, and HIV protease inhibitors): may raise blood concentrations and increase side effect risk.
  • CYP3A4 inducers (for example rifampin): may lower effectiveness by reducing blood levels.
  • Alcoholic liquid can increase dizziness and lower blood pressure; avoid heavy drinking when using these agents.
  • Grapefruit juice can increase tadalafil exposure and should generally be limited or avoided.

Missed today protocol

Because the combination is usually taken on an as-needed basis, missing a dose is uncommon. If your clinician prescribes a regular dosing schedule, follow their instructions and do not double the next dose to compensate for a missed tablet.

When an overdose incident occurs

In the event of suspected suspected overdose, seek emergency medical care immediately. Symptoms that may indicate suspected overdose include:

  • Severe nausea, repeated vomiting
  • Prolonged or painful erection (priapism)
  • Chest pain with a fast heart rate or irregular rhythm.
  • Severe dizziness, fainting, or dangerously low blood pressure
  • Excessive bleeding from the nose, severe flushing, or extreme dry mouth

Take the medication container or a picture of the label with you to the emergency department so clinicians can identify the active ingredients and doses.

Preserve and handle

  • Keep tablets in the original sealed container at room temperature away from moisture.
  • Protect from excessive heat and direct sunlight.
  • Store all medicines where children and pets cannot reach them.

Different courses of action and comparable treatments

If you need treatment for ED or PE, US-licensed clinicians commonly recommend the following options, alone or in combination depending on individual needs:

  • Tadalafil alone (generic tadalafil or brand Cialis) — FDA-approved for ED and, in some doses, for benign prostatic hyperplasia; available for on-demand use or in a daily low-dose formulation.
  • Sildenafil (generic sildenafil or brand Viagra) — an on-demand PDE5 inhibitor with a shorter duration for many men.
  • Vardenafil (Levitra) and avanafil (Stendra) — a different possibility PDE5 inhibitors; avanafil is sometimes chosen for faster onset.
  • Topical anesthetic options for premature ejaculation such as lidocaine-prilocaine creams or sprays to reduce penile sensitivity.
  • Oral SSRIs like sertraline or paroxetine are sometimes used off-label for PE; they are generic and often covered by insurance when prescribed for approved symptoms.
  • Nonpharmacologic approaches such as behavioral techniques (start-stop, squeeze), pelvic floor exercises, and sex therapy or counseling can be effective and are safe adjuncts.

Note: dapoxetine (sold as Priligy in some countries) is not FDA-approved in the United States. Many US clinicians will combine an FDA-approved ED medication with a topical anesthetic or consider an SSRI where clinically appropriate. All treatment choices should be made under the supervision of a licensed prescriber.

Typical costs in the United States (USD)

The following are rough out-of-pocket ranges in US american dollars. Actual prices depend on pharmacy, location, dose, patient assistance programs, and insurance coverage.

  • Extra Super Tadarise (40 mg tadalafil + 60 mg dapoxetine): this combination is not approved for sale in the United States and is not dispensed by US pharmacy centers. Online listings from foreign sellers commonly quote about 3 to 8 USD per tablet, but authenticity and legality are uncertain. See Legal memos.
  • Generic tadalafil (10 to 20 mg): with discount programs often about 1 to 5 USD per tablet; brand Cialis without discounts may cost 20 to 60 USD per tablet.
  • Generic sildenafil (50 to 100 mg): approximately 0.50 to 2 USD per tablet with savings; brand Viagra is considerably more expensive.
  • Avanafil (Stendra): typical brand prices often range from 15 to 40 USD per tablet.
  • Topical lidocaine-prilocaine products for PE: roughly 20 to 40 USD per month depending on product and use frequency.
  • Generic SSRIs (used off-label for PE): usually low cost when generic and may be covered by insurance for approved outward signs.

Out-of-pocket costs can be reduced with insurance coverage, manufacturer coupons, pharmacy discount cards, and telehealth prescribing services for FDA-approved drugs. Purchasing unapproved products from overseas carries additional shipping, customs, and safety risks and may result in seizure or disposal by authorities.

Additional aspects about Extra Super Tadarise